At Precise Mind, we seek to empower you with knowledge about the treatment and procedures you are considering. Treatment-resistant depression often feels difficult to manage. However, our providers are here to partner with you through every step of the process as you consider treatment options, such as Spravato.
Our team can explain the Spravato process in detail, covering the possible results you may experience and answering commonly asked questions, such as “What is the success rate of Spravato treatment?” We are happy to help you make an informed decision. With offices in Flowood, Vicksburg, Ridgeland, and Byram, we strive to offer accessible care to everyone in our community.
The goal of Spravato is to manage the brain’s levels of the neurotransmitter glutamate. Glutamate helps regulate mood and may contribute to depression if dysregulated. The medication works by blocking the N-methyl-D-aspartate receptors to help restore balance to the glutamate system. Spravato is administered as a nasal spray under the supervision of a medical professional, who will monitor your response and manage any side effects that may arise.
During your first few sessions, you typically receive the medicine twice a week, allowing its therapeutic effects to work more quickly. Eventually, the frequency of treatment may be reduced. Everyone responds to Spravato differently and our team is committed to helping you get the most out of your treatment. Our providers will help you find the treatment plan that works best for you.
Several studies have highlighted the effectiveness of Spravato in helping treatment-resistant depression. One analysis, the TRANSFORM-2 trial, found that treatment-resistant depression patients who had undergone Spravato saw meaningful improvement on the Montgomery-Åsberg Depression Rating Scale (MADRS) within four weeks of beginning treatment (Daly et al., 2019; Popova et al., 2019).
Another study found that patients with treatment-resistant depression who received Spravato had healthier scores on the Patient Health Questionnaire-9 (PHQ-9), in comparison to those who did not follow the treatment (Wajs et al., 2020).
There are a variety of reasons Spravato’s success rate may vary from patient to patient, and everyone’s results are unique. Factors that may influence treatment results include:
Additionally, combining Spravato with other therapies can lead to better treatment results. It may be used together with oral antidepressants or psychotherapy to manage different aspects of depression. This combination sometimes leads to better outcomes. Your provider will help determine if a combined approach like this meets your needs and health goals.
So, what is the success rate of Spravato treatment? Everyone is unique and responds to treatment at different rates. At Precise Mind, our providers will discuss any questions you have and work with you to determine if Spravato is a good option for managing your depression. Contact us today to feel empowered with knowledge about the treatment you choose.